HPLC Column, IEX WCX, 10um, 4.6mm ID x 100mm Length, 100A. Cogent Brand. 1 EA.
Additional Information:
Cogent IEX WCX is a weak cation exchange (WCX) HPLC stationary phase manufactured using high-purity silica and carboxylic acid functional groups that provide pH-dependent negative charge characteristics. This weak cation exchange mechanism offers selective retention and separation of positively charged analytes while allowing greater control of retention through mobile phase pH adjustments. The stationary phase is particularly useful for basic compounds, amines, peptides, and other cationic species and serves as an excellent alternative for USP L9 methods requiring weak cation exchange selectivity.
67091-10P is a 100 mm x 4.6 mm ID analytical column packed with 10 µm WCX particles with a 100 Å pore size. The 100 mm length provides an excellent balance between chromatographic resolution and analysis time, while the larger 10 µm particle size delivers low backpressure and supports higher flow rates compared to smaller particle packings. Typical operating flow rates are approximately 1.0–3.0 mL/min, making this column well suited for conventional HPLC systems and routine ion exchange applications.
This USP L9 column is particularly useful for the separation and purification of positively charged compounds, including basic pharmaceuticals, amines, peptides, alkaloids, and other cationic species. The weak cation exchange functionality allows chromatographers to optimize selectivity through pH control while maintaining excellent efficiency and reproducibility.
Key Benefits
Weak cation exchange (WCX) stationary phase
Carboxylic acid functional groups
pH-dependent retention characteristics
Suitable alternative for USP L9 methods
10 µm particles for lower backpressure
Supports higher flow rates
Balanced resolution and analysis time
High-purity silica support
Typical Applications
USP L9 methods
Ion exchange chromatography
Basic compound analysis
Pharmaceutical analysis
Amine separations
Peptide analysis
Method development
Quality control testing
Specifications
Product Type: HPLC Column
Stationary Phase: IEX WCX
USP Classification: L9
Chromatography Mode: Weak Cation Exchange
Functional Group: Carboxylic Acid
Functional pH Range: Approximately pH 2.5–7
Particle Size: 10 µm
Pore Size: 100 Å
Column Dimensions: 4.6 mm ID x 100 mm
Length: 100 mm
Recommended Flow Rate: 1.0–3.0 mL/min
Brand: Cogent
Important Notes
Designed for ion exchange chromatography
Retains positively charged analytes
Retention can be adjusted through mobile phase pH control
100 mm length balances resolution and run time
Lower backpressure compared to smaller particle columns
Supports higher flow rates for routine methods
Excellent alternative for many USP L9 methods
Particularly useful for basic compounds and amine-containing analytes